Technology development of hyperthermic pressurized intraperitoneal aerosol chemotherapy (hPIPAC)
نویسندگان
چکیده
منابع مشابه
Pressurized intraperitoneal aerosol chemotherapy (PIPAC) as a neoadjuvant therapy before cytoreductive surgery and hyperthermic intraperitoneal chemotherapy
BACKGROUND Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a novel drug delivery system able to induce regression of peritoneal metastasis (PM) in the salvage situation. The aim of this study was to determine the clinical characteristics, tumor histology, and extent of disease of the patients having undergone cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy ...
متن کاملInflammatory Response and Toxicity After Pressurized IntraPeritoneal Aerosol Chemotherapy
Background: Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) is a novel mode of intraperitoneal (IP) drug delivery claiming high IP tissue concentrations with low systemic uptake. The aim was to study inflammatory response and systemic toxicity after PIPAC. Methods: Retrospective monocentric analysis of a consecutive cohort of PIPAC patients between January 2015 and April 2016. Detailed...
متن کاملHyperthermic Intraperitoneal Chemotherapy
Selected patients with peritoneal surface malignancies benefit from a radical therapeutic approach consisting of cytoreductive surgery combined with perioperative intraperitoneal chemotherapy (PIC), whichmay be complemented by systemic chemotherapy. Numerous studies have shown the efficacy of this strategy, which has led to survival results unknown to date, even in the era of last-generation ch...
متن کاملNanoparticle as a novel tool in hyperthermic intraperitoneal and pressurized intraperitoneal aerosol chemotheprapy to treat patients with peritoneal carcinomatosis
The treatment of peritoneal surface malignances has changed considerably over the last thirty years. Unfortunately, the palliative is the only current treatment for peritoneal carcinomatosis (PC). Two primary intraperitoneal chemotherapeutic methods are used. The first is combination of cytoreductive surgery (CRS) and Hyperthermic IntraPEritoneal Chemotherapy (HIPEC), which has become the gold ...
متن کاملClinical delivery system for intraperitoneal hyperthermic chemotherapy.
A 35-year-old man was treated for pseudomyxoma peritonei by surgery and by thermal infusion and chemotherapy with a machine designed specifically for the treatment of cancers of serosal surfaces. After extensive abdominal resection and closure, the patient's peritoneal cavity was instilled with 2.5 liters of 5% lactated Ringer's solution. He was then attached to hyperthermic perfusion system wh...
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ژورنال
عنوان ژورنال: Surgical Endoscopy
سال: 2021
ISSN: 0930-2794,1432-2218
DOI: 10.1007/s00464-021-08567-y